Solvent-free synthesis of 4,4-bis-functionalized-1,6-dienes and 1,6-diynes on the surface of neutral alumina

被引：24
作者：
Bhar, S [1 ]
Chaudhuri, SK [1 ]
Sahu, SG [1 ]
Panja, C [1 ]
机构：
[1] Jadavpur Univ, Fac Sci, Dept Chem, Organ Chem Sect, Kolkata 700032, W Bengal, India
来源：
TETRAHEDRON | 2001年 / 57卷 / 43期
关键词：
regiocontrol; solid-phase synthesis; supported reagents; dienes and diynes;
D O I：
10.1016/S0040-4020(01)00896-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An improved procedure has been developed for the synthesis of structurally varied 4,4-bis-functionalized-1,6-dienes and 1,6-diynes through regioselective alkylation of active methylene compounds with several unsymmetrical allyl bromides and propargyl bromide on the surface of neutral alumina impregnated with sodium ethoxide or potassium tert-butoxide in the absence of any solvent under environmentally benign conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：9011 / 9016
页数：6
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