Gender Identity Disorder in Twins: A Review of the Case Report Literature

被引：105

作者：

Heylens, Gunter ^{[1
]}

De Cuypere, Griet ^{[1
]}

Zucker, Kenneth J. ^{[2
]}

Schelfaut, Cleo ^{[3
]}

Elaut, Els ^{[1
]}

Vanden Bossche, Heidi ^{[4
]}

De Baere, Elfride ^{[5
]}

T'Sjoen, Guy ^{[1
,3
]}

机构：

[1] Ghent Univ Hosp, Dept Sexol & Gender Problems, B-9000 Ghent, Belgium

[2] Ctr Addict & Mental Hlth, Gender Ident Serv, Child Youth & Family Program, Toronto, ON, Canada

[3] Ghent Univ Hosp, Dept Endocrinol, Ghent, Belgium

[4] Ghent Univ Hosp, Child & Adolescent Gender Clin, Ghent, Belgium

[5] Ghent Univ Hosp, Ctr Med Genet, Ghent, Belgium

来源：

JOURNAL OF SEXUAL MEDICINE | 2012年 / 9卷 / 03期

关键词：

Twins; Gender Identity Disorder; Genetics; Biologic Factors in GID; Transsexualism; MONOZYGOTIC TWINS; PAIRS DISCORDANT; TRANSSEXUALISM; CONCORDANT; CHILD; PREVALENCE; DYSPHORIA; GIRLS;

D O I：

10.1111/j.1743-6109.2011.02567.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction. The etiology of gender identity disorder (GID) remains largely unknown. In recent literature, increased attention has been attributed to possible biological factors in addition to psychological variables. Aim. To review the current literature on case studies of twins concordant or discordant for GID. Methods. A systematic, comprehensive literature review. Results. Of 23 monozygotic female and male twins, nine (39.1%) were concordant for GID; in contrast, none of the 21 same-sex dizygotic female and male twins were concordant for GID, a statistically significant difference (P = 0.005). Of the seven opposite-sex twins, all were discordant for GID. Conclusions. These findings suggest a role for genetic factors in the development of GID. Heylens G, De Cuypere G, Zucker KJ, Schelfaut C, Elaut E, Vanden Bossche H, De Baere E, and T'Sjoen G. Gender identity disorder in twins: A review of the case report literature. J Sex Med 2012; 9: 751-757.

引用

页码：751 / 757

页数：7

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