Al(OTf)3 as a new efficient catalyst for the direct nucleophilic substitution of ferrocenyl alcohol substrates. Convenient preparation of ferrocenyl-PEG compounds

被引：9

作者：

Allali, Naoual ^{[1
]}

Mamane, Victor ^{[1
]}

机构：

[1] Univ Lorraine, CNRS UMR 7565, Lab SRSMC, F-54506 Vandoeuvre Les Nancy, France

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 21期

关键词：

Nucleophilic substitution; Ferrocene; Aluminium triflate; PEG; Catalysis; SOLVENT-FREE CONDITIONS; LEWIS-ACID CATALYST; ALUMINUM TRIFLATE; RECYCLABLE CATALYST; ORGANIC-SYNTHESIS; HYDROXY GROUP; PHENOLS; CARBON; AMINOLYSIS; BIOSENSORS;

D O I：

10.1016/j.tetlet.2012.03.042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of Al(OTf)(3) as a new efficient catalyst for the direct nucleophilic substitution of the hydroxy group of ferrocenyl alcohols is described. This catalyst, originally developed for the mono-substitution of ethylene glycol nucleophiles of different length has shown a high activity with other carbon-, nitrogen-, and sulfur-based nucleophiles. In all the studied cases, no more than 1 mol % of catalyst was needed to allow fast and clean reactions. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：2604 / 2607

页数：4

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