Beyond drug use: a systematic consideration of other outcomes in evaluations of treatments for substance use disorders

被引:158
作者
Tiffany, Stephen T. [1 ]
Friedman, Lawrence [3 ]
Greenfield, Shelly F. [2 ,4 ]
Hasin, Deborah S. [5 ]
Jackson, Ron [6 ]
机构
[1] SUNY Buffalo, Dept Psychol, Buffalo, NY 14260 USA
[2] McLean Hosp, Belmont, MA 02178 USA
[3] SUNY Buffalo, Buffalo, NY 14260 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
[5] Columbia Univ, New York, NY USA
[6] Evergreen Treatment Serv, Seattle, WA USA
关键词
Addiction treatment; clinical outcomes; measures; recommendations; QUALITY-OF-LIFE; NATIONAL EPIDEMIOLOGIC SURVEY; ABSTINENCE SELF-EFFICACY; SMOKING-CESSATION; CLINICAL-TRIALS; INITIAL VALIDATION; SOCIAL SUPPORT; UNITED-STATES; HEROIN USERS; DSM-IV;
D O I
10.1111/j.1360-0443.2011.03581.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Across the addictions field, the primary outcome in treatment research has been reduction in drug consumption. A comprehensive view of the impact of substance use disorders on human functioning suggests that effective treatments should address the many consequences and features of addiction beyond drug use, a recommendation forwarded by multiple expert panels and review papers. Despite recurring proposals, and a compelling general rationale for moving beyond drug use as the sole standard for evaluating addiction treatment, the field has yet to adopt any core set of other measures that are routinely incorporated into treatment research. Among the many reasons for the limited impact of previous proposals has been the absence of a clear set of guidelines for selecting candidate outcomes. This paper is the result of the deliberations of a panel of substance abuse treatment and research experts convened by the National Institute on Drug Abuse to discuss appropriate outcome measures for clinical trials of substance abuse treatments. This paper provides an overview of previous recommendations and outlines specific guidelines for consideration of candidate outcomes. A list of outcomes meeting those guidelines is described and illustrated in detail with two outcomes: craving and quality of life. The paper concludes with specific recommendations for moving beyond the outcome listing offered in this paper to promote the programmatic incorporation of these outcomes into treatment research.
引用
收藏
页码:709 / 718
页数:10
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