New reactions with thiosulfines/dithiiranes: Cycloadditions leading to dispiro derivatives of 1,2,4-trithiolane

被引：16

作者：

Hegab, MI

Abdel-Megeid, FME

Gad, FA

Shiba, SA

Sotofte, I

Moller, J

Senning, A ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Appl Chem, DK-2800 Lyngby, Denmark

[2] Natl Res Ctr, Cairo, Egypt

[3] Ain Shams Univ, Fac Sci, Dept Chem, Cairo, Egypt

[4] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark

[5] Odense Univ, Dept Chem, DK-5230 Odense, Denmark

来源：

ACTA CHEMICA SCANDINAVICA | 1999年 / 53卷 / 02期

关键词：

D O I：

10.3891/acta.chem.scand.53-0133

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The beta-oxo thiosulfines 8, generated by 'unzipping' of the corresponding acetyl alpha-chloroalkyl disulfides 11 with morpholine, are partially converted into the corresponding thioketones 12 which then cycloadd to 8 to give the observed cis-and trans-1,2,4-trithiolanes 15. The unsymmetrical Diels-Alder dimerization of 12 plays only a minor role. The new heterocycles thus obtained have been characterized spectroscopically and by X-ray crystallography.

引用

页码：133 / 140

页数：8

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