Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, July 2019-February 2020

被引：66

作者：

Alleman, Mary M. ^{[1
]}

Jorba, Jaume ^{[2
]}

Greene, Sharon A. ^{[1
,3
]}

Diop, Ousmane M. ^{[4
]}

Iber, Jane ^{[2
]}

Tallis, Graham ^{[4
]}

Goel, Ajay ^{[4
]}

Wiesen, Eric ^{[1
]}

Wassilak, Steven G. F. ^{[1
]}

Burns, Cara C. ^{[2
]}

机构：

[1] CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA

[2] CDC, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA

[3] CDC, Epidem Intelligence Serv, Atlanta, GA 30333 USA

[4] WHO, Polio Eradicat Dept, Geneva, Switzerland

来源：

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT | 2020年 / 69卷 / 16期

关键词：

D O I：

10.15585/mmwr.mm6916a1

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

What is already known about this topic? Circulating vaccine-derived polioviruses (cVDPVs) can emerge in settings with low poliovirus immunity and can cause paralysis. What is added by this report? Thirty-one ongoing and new cVDPV type 2 (cVDPV2) outbreaks were documented during July 2019-February 2020; nine outbreaks spread internationally. New cVDPV2 outbreaks were often linked to poor coverage with monovalent Sabin oral poliovirus vaccine (OPV) type 2 during outbreak response campaigns. What are the implications for public health practice? The Global Polio Eradication Initiative plans to introduce a genetically stabilized, novel OPV type 2 for outbreak response in mid-2020 and expand use in 2021. Cessation of all OPV use after certification of polio eradication will eliminate the risk of VDPV emergence.

引用

页码：489 / 495

页数：7

共 9 条

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