Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, July 2019-February 2020

被引:67
作者
Alleman, Mary M. [1 ]
Jorba, Jaume [2 ]
Greene, Sharon A. [1 ,3 ]
Diop, Ousmane M. [4 ]
Iber, Jane [2 ]
Tallis, Graham [4 ]
Goel, Ajay [4 ]
Wiesen, Eric [1 ]
Wassilak, Steven G. F. [1 ]
Burns, Cara C. [2 ]
机构
[1] CDC, Global Immunizat Div, Ctr Global Hlth, Atlanta, GA 30333 USA
[2] CDC, Div Viral Dis, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA
[3] CDC, Epidem Intelligence Serv, Atlanta, GA 30333 USA
[4] WHO, Polio Eradicat Dept, Geneva, Switzerland
来源
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT | 2020年 / 69卷 / 16期
关键词
D O I
10.15585/mmwr.mm6916a1
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
What is already known about this topic? Circulating vaccine-derived polioviruses (cVDPVs) can emerge in settings with low poliovirus immunity and can cause paralysis. What is added by this report? Thirty-one ongoing and new cVDPV type 2 (cVDPV2) outbreaks were documented during July 2019-February 2020; nine outbreaks spread internationally. New cVDPV2 outbreaks were often linked to poor coverage with monovalent Sabin oral poliovirus vaccine (OPV) type 2 during outbreak response campaigns. What are the implications for public health practice? The Global Polio Eradication Initiative plans to introduce a genetically stabilized, novel OPV type 2 for outbreak response in mid-2020 and expand use in 2021. Cessation of all OPV use after certification of polio eradication will eliminate the risk of VDPV emergence.
引用
收藏
页码:489 / 495
页数:7
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