MicroRNAs, damage levels, and DNA damage response control

被引：5
作者：
Visser, Hartwig [1 ]
Thomas, Adam D. [1 ]
机构：
[1] Univ West England, Ctr Res Biosci, Coldharbour Lane, Bristol BS16 1QY, Avon, England
来源：
TRENDS IN GENETICS | 2021年 / 37卷 / 11期
关键词：
P53; ATM; PHOSPHORYLATION; INDUCTION;
D O I：
10.1016/j.tig.2021.06.018
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
DNA damage-inducible miRNAs are likely to be functional in the DNA damage response. This response can elicit damage resolution and cell survival or apoptosis. The current, albeit incomplete, picture suggests that miRNAs can affect cell fate via modulation of key response proteins, but the question is, who's in charge?
引用
收藏
页码：963 / 965
页数：3
相关论文
共 50 条
  • [41] Targeting the DNA Damage Response in Cancer
    Ljungman, Mats
    CHEMICAL REVIEWS, 2009, 109 (07) : 2929 - 2950
  • [42] MKK7 and ARF New players in the DNA damage response scenery
    Kotsinas, Athanassios
    Papanagnou, Panagiota
    Galanos, Panagiotis
    Schramek, Daniel
    Townsend, Paul
    Penninger, Josef M.
    Bartek, Jiri
    Gorgoulis, Vassilis G.
    CELL CYCLE, 2014, 13 (08) : 1227 - 1236
  • [43] Inhibition of Aurora A in response to DNA damage
    A Krystyniak
    C Garcia-Echeverria
    C Prigent
    S Ferrari
    Oncogene, 2006, 25 : 338 - 348
  • [44] Historical perspective on the DNA damage response
    Hanawalt, Philip C.
    DNA REPAIR, 2015, 36 : 2 - 7
  • [45] Causes and consequences of the DNA damage response
    Nussenzweig, Andre
    CELL CYCLE, 2007, 6 (19) : 2339 - 2340
  • [46] Polyomavirus interaction with the DNA damage response
    Justice, Joshua L.
    Verhalen, Brandy
    Jiang, Mengxi
    VIROLOGICA SINICA, 2015, 30 (02) : 122 - 129
  • [47] The response to DNA damage in heterochromatin domains
    Fortuny, Anna
    Polo, Sophie E.
    CHROMOSOMA, 2018, 127 (03) : 291 - 300
  • [48] Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development
    Gill, Sonja J.
    Wijnhoven, Paul W. G.
    Fok, Jacqueline H. L.
    Lloyd, Rebecca L.
    Cairns, Jonathan
    Armenia, Joshua
    Nikkila, Jenni
    Lau, Alan
    Bakkenist, Christopher J.
    Galbraith, Susan M.
    Vens, Conchita
    O'Connor, Mark J.
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (09) : 1614 - 1626
  • [49] Dyskerin, telomerase and the DNA damage response
    Gu, BaiWei
    Bessler, Monica
    Mason, Philip J.
    CELL CYCLE, 2009, 8 (01) : 6 - 10
  • [50] DNA damage response and hematological malignancy
    Takagi, Masatoshi
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017, 106 (03) : 345 - 356
12345