Exogenous interleukin-15 enhances immune function of umbilical cord blood (CB) mononuclear cells (MNC) by up-regulating cytokine production and NK, LAK, and CTL activities.

被引：0

作者：

Qian, JX ^{[1
]}

Suen, Y ^{[1
]}

vandeVen, C ^{[1
]}

Knoppel, E ^{[1
]}

Cairo, MS ^{[1
]}

机构：

[1] CHILDRENS HOSP ORANGE CTY,ORANGE,CA 92668

来源：

BLOOD | 1996年 / 88卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1246 / 1246

页数：1

共 9 条

[1] Decreased interleukin-15 from activated cord versus adult peripheral blood mononuclear cells and the effect of interleukin-15 in upregulating antitumor immune activity and cytokine production in cord blood
Qian, JX
Lee, SM
Suen, Y
Knoppel, E
vandeVen, C
Cairo, MS
BLOOD, 1997, 90 (08) : 3106 - 3117
[2] Interleukin-15 enhances CD4+ CD45RA+ expression on umbilical cord blood mononuclear cells
Lin, SJ
Chao, HC
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2001, 12 (04) : 188 - 193
[3] Interleukin-15 enhances the expansion and function of natural killer T cells from adult peripheral and umbilical cord blood
Lin, Syh-Jae
Huang, Ying-Cheng
Cheng, Po-Jen
Lee, Pei-Tzu
Hsiao, Hsiu-Shan
Kuo, Ming-Ling
CYTOKINE, 2015, 76 (02) : 348 - 355
[4] Decreased interleukin-15 (IL-15) expression from activated cord (C) vs adult (A) peripheral blood (PB) mononuclear cells (MNC): Implication in the immaturity of cord blood immune regulation.
Lee, S
Sweetman, R
Suen, Y
Knoppel, E
Cairo, MS
BLOOD, 1996, 88 (10) : 618 - 618
[5] IL-12 enhanced IFN-gamma protein production, NK and LAK cytotoxicity in cord monocyte depleted mononuclear cells (MD-MNC): Potential for immunotherapy post cord blood (CB) transplantation
Suen, Y
Chang, L
Qian, J
Bruner, V
Knoppel, E
vandeVen, C
Cairo, MS
BLOOD, 1995, 86 (10) : 3898 - 3898
[6] Down regulation of interleukin 12 (IL-12) and interleukin 15 (IL-15) gene expression and protein production in activated cord vs adult peripheral blood (APB) mononuclear cells (MNC) but up regulation by IL-12 and IL-15 cord blood (CB) anti-tumor immune activity
Cairo, MS
Lee, SM
Suen, Y
Qian, JX
Knoppel, E
vandeVen, C
EXPERIMENTAL HEMATOLOGY, 1997, 25 (08) : 357 - 357
[7] Significant downregulation of interleukin (IL-)-18 gene expression and protein production in constitutive and activated umbilical cord blood (CB) vs. adult peripheral blood (APB) mononuclear cells (MNC): Potential mechanism for differential alloreactivity.
Wu, J
Cairo, S
van de Ven, C
Suri, MS
Baxi, LV
Cairo, MS
BLOOD, 2001, 98 (11) : 205A - 205A
[8] Decreased interleukin-15 (IL-15) mRNA expression from activated cord (C) vs adult (A) peripheral blood (PB) mononuclear cells (NC): Implication in the immaturity of neonatal immune function and decreased graft-vs-host disease (GvHD) post cord blood transplant (CBT)
Sweetman, R
Lee, SM
Knoppel, E
Cairo, MS
PEDIATRIC RESEARCH, 1996, 39 (04) : 963 - 963
[9] Significant downregulation of interleukin (IL)-18 gene expression and protein production and IL-18 induced IFN-γ production in activated cord blood (CB) vs. adult peripheral blood (APB) mononuclear cells (MNC) may be secondary to posttranscriptional dysregulation:: Potential mechanism for differences in CB vs. APB immune reconstitution and aGVHD.
Wu, J
Ayello, J
Cairo, S
van De Ven, C
Suri, M
Baxi, LV
Cairo, MS
BLOOD, 2002, 100 (11) : 51B - 51B

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