Subjective effects of combustible, vaporized, and edible cannabis: Results from a survey of adolescent cannabis users

被引:18
作者
Boisvert, Esthelle Ewusi [1 ]
Bae, Dayoung [2 ]
Pang, Raina D. [3 ]
Davis, Jordan P. [4 ]
Kelley-Quon, Lorraine I. [3 ,5 ,6 ]
Barrington-Trimis, Jessica L. [3 ]
Kirkpatrick, Matthew G. [3 ]
Chai, Stephanie H. [3 ]
Leventhal, Adam M. [1 ,3 ]
机构
[1] Univ Southern Calif, Dept Psychol, Los Angeles, CA 90007 USA
[2] Korea Univ, Dept Home Econ Educ, Coll Educ, Seoul, South Korea
[3] Univ Southern Calif, Dept Prevent Med, Los Angeles, CA 90007 USA
[4] USC, Ctr Artificial Intelligence Soc, Suzanne Dworak Peck Sch Social Work, Dept Children Youth & Families, Los Angeles, CA USA
[5] Childrens Hosp Los Angeles, Div Pediat Surg, Los Angeles, CA 90027 USA
[6] Univ Southern Calif, Keck Sch Med, Dept Surg, Los Angeles, CA 90007 USA
关键词
Cannabis; Subjective effects; Adolescents; Combustible; Vaporized; Edible; MARIJUANA USE; ELECTRONIC CIGARETTES; ORAL CANNABIS; UNITED-STATES; LEGALIZATION; SMOKING; ALCOHOL; TOBACCO; DRUGS; BLOOD;
D O I
10.1016/j.drugalcdep.2019.107716
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Background: Data from controlled laboratory experiments in adults indicate that the subjective effects of cannabis vary by administration method (e.g., combustible, vaporized). Whether the subjective effects of cannabis experienced in the natural ecology and among adolescents differ by cannabis administration method is unknown. In this observational study, adolescents' retrospective reports of subjective effects after combustible, edible, and vaporized cannabis use were examined. Methods: Students from ten public schools in Los Angeles, CA, USA (M[SD] age = 16.1 [.43] years) who reported past 6-month use of combustible, edible, or vaporized cannabis (N = 584) were surveyed on subjective effects experienced after use (yes/no). They were provided with a 12 item self-report checklist of six positive (e.g., relaxed, energetic) and six negative (e.g., drowsy, lazy) subjective effects. For each method of administration, affirmative responses were summed in positive (range: 0-6) and negative (range: 0-6) effect composite scores. Results: Generalized estimating equations adjusted for demographics and recent cannabis use revealed a graded pattern of differences in positive subjective effects across products, with highest scores for combustible (M [SD] = 3.98[1.76]), followed by edible (M[SD] = 3.58 [2.04]) and vaporized (M[SD] = 3.11 [2.21]) cannabis (all pairwise cross-product contrasts p < .01). Mean negative effect score was highest for edible (M[SD] = 2.27 [1.95]), followed by combustible (M[SD] = 1.94 [1.66]), and vaporized (M[SD] = 1.34 [1.73]) cannabis, respectively (all pairwise contrasts p < .02). Conclusion: Adolescents' reports of subjective effects varied across cannabis administration methods. Combustible cannabis' more desirable subjective effects profile might be indicative of higher abuse liability.
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页数:6
相关论文
共 42 条
[21]   Differences in reporting of perceived acute effects of alcohol use, marijuana use, and simultaneous alcohol and marijuana use [J].
Lee, Christine M. ;
Cadigan, Jennifer M. ;
Patrick, Megan E. .
DRUG AND ALCOHOL DEPENDENCE, 2017, 180 :391-394
[22]   Online survey characterizing vaporizer use among cannabis users [J].
Lee, Dustin C. ;
Crosier, Benjamin S. ;
Borodovsky, Jacob T. ;
Sargent, James D. ;
Budney, Alan J. .
DRUG AND ALCOHOL DEPENDENCE, 2016, 159 :227-233
[23]   Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence [J].
Leventhal, Adam M. ;
Strong, David R. ;
Kirkpatrick, Matthew G. ;
Unger, Jennifer B. ;
Sussman, Steve ;
Riggs, Nathaniel R. ;
Stone, Matthew D. ;
Khoddam, Rubin ;
Samet, Jonathan M. ;
Audrain-McGovern, Janet .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2015, 314 (07) :700-707
[24]  
Lyons MJ, 1997, ADDICTION, V92, P409
[25]   Half-Baked - The Retail Promotion of Marijuana Edibles [J].
MacCoun, Robert J. ;
Mello, Michelle M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (11) :989-991
[26]   Experiences of Marijuana-Vaporizer Users [J].
Malouff, John M. ;
Rooke, Sally E. ;
Copeland, Jan .
SUBSTANCE ABUSE, 2014, 35 (02) :127-128
[27]  
Miech R.A., 2018, Monitoring the Future national survey results on drug use, 1975-2017: Volume I, Secondary school students, V1, P1
[28]   High School Students' Use of Electronic Cigarettes to Vaporize Cannabis [J].
Morean, Meghan E. ;
Kong, Grace ;
Camenga, Deepa R. ;
Cavallo, Dana A. ;
Krishnan-Sarin, Suchitra .
PEDIATRICS, 2015, 136 (04) :611-616
[29]   Subjective and physiological effects, and expired carbon monoxide concentrations in frequent and occasional cannabis smokers following smoked, vaporized, and oral cannabis administration [J].
Newmeyer, Matthew N. ;
Swortwood, Madeleine J. ;
Abulseoud, Osama A. ;
Huestis, Marilyn A. .
DRUG AND ALCOHOL DEPENDENCE, 2017, 175 :67-76
[30]   Subjective Cannabis Effects as Part of a Developing Disorder in Adolescents and Emerging Adults [J].
Padovano, Hayley Treloar ;
Miranda, Robert, Jr. .
JOURNAL OF ABNORMAL PSYCHOLOGY, 2018, 127 (03) :282-293