Phenothiazine-aminothiourea-Hg(II) ensemble-based fluorescence turn-on toward iodide in aqueous media and imaging application in live cells

被引：42

作者：

Yang, Wenge ^{[1
,2
]}

Yang, Shouhai ^{[1
]}

Guo, Qirun ^{[1
]}

Zhang, Tuan ^{[1
]}

Wu, Keyi ^{[1
]}

Hu, Yonghong ^{[1
]}

机构：

[1] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, Nanjing 210009, Jiangsu, Peoples R China

[2] Jiangsu Engn Technol Res Ctr Polypeptide Pharmace, Nanjing 210038, Jiangsu, Peoples R China

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2015年 / 213卷

关键词：

Phenothiazine (PTH); Mercury; Iodide; Human Umbilical Vein Endothelial Cells (HUVEC); SENSOR; IONS; CHEMODOSIMETER; PROBE; CU2+;

D O I：

10.1016/j.snb.2015.02.117

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A phenothiazine-aminothiourea-based open chemosensor (P1) has been designed and synthesized, which exhibits high selectivity toward Hg2+ by forming a 1:1 complex. In its Hg2+ ensemble, it is reported as a highly sensitive and selective probe for the detection of iodide based on the displacement approach in aqueous solution. The addition of iodide to a solution of phenothiazine-aminothiourea-Hg2+ ensemble resulted in a rapid and remarkable fluorescence off-on (emission at 565 nm). The practical use of an 'ensemble' was demonstrated by its application to the detection of iodide in the living cells. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：404 / 408

页数：5

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