Vitamin A: Is it a risk factor for osteoporosis and bone fracture?

被引：0
作者：
Ribaya-Mercado, Judy D. [1 ]
Blumberg, Jeffrey B. [1 ]
机构：
[1] Tufts Univ, Jean Mayer USDA, Human Nutr Res Ctr Aging, Boston, MA 02111 USA
来源：
NUTRITION REVIEWS | 2007年 / 65卷 / 10期
关键词：
vitamin A; retinol; bone; osteoporosis; fracture;
D O I：
10.1301/nr.2007.oct.425-438
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Results from observational studies of the association between vitamin A intake or serum concentration and bone mineral density or fracture are mixed. The inconsistencies may be due, in part, to difficulties in obtaining an accurate assessment of vitamin A intake or status. Serum retinol is a poor measure of vitamin A status because it is subject to homeostatic control. Stable- isotope-dilution methodology gives a validated assessment of the total-body and liver vitamin A stores and is recommended in future studies on vitamin A status and osteoporosis. The potential for exacerbating an already serious public health problem with intakes of vitamin A currently considered safe indicates further research into this matter is warranted. Key words: vitamin A, retinol, bone, osteoporosis, fracture (C) 2007 International Life Sciences Institute
引用
收藏
页码：425 / 438
页数：14
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