Pd-Catalyzed Three-Component Coupling of N-Tosylhydrazone, Terminal Alkyne, and Aryl Halide

被引：184

作者：

Zhou, Lei ^{[1
]}

Ye, Fei ^{[1
]}

Zhang, Yan ^{[1
]}

Wang, Jianbo ^{[1
]}

机构：

[1] Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Coll Chem, Minist Educ,BNLMS, Beijing 100871, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 39期

基金：

中国博士后科学基金;

关键词：

CARBENE INSERTION; VINYL HALIDES; DIAZOESTERS; REAGENTS; BROMIDES;

D O I：

10.1021/ja105762n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Pd-catalyzed three-component reaction of N-tosylhydrazone, terminal alkyne, and aryl halide follows a mechanism involving a sequence of Pd carbene migratory insertion-trans-metalation reductive elimination, leading to the formation of one sp(2)-sp(3) C-C bond and one sp-sp(3) C-C bond.

引用

页码：13590 / 13591

页数：2

共 28 条

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