Commentary on Verweij et al. (2016): Conduct problems and substance use-genetic and environmental perspectives on sex differences

被引:0
作者
Few, Lauren R. [1 ]
Agrawal, Arpana [1 ]
机构
[1] Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
关键词
Adolescence; cannabis; conduct; correlation; Finntwin; tobacco; twin; GENOME-WIDE ASSOCIATION; BEHAVIORAL DISINHIBITION; ANTISOCIAL-BEHAVIOR; CANNABIS USE; DISORDER; ALCOHOL;
D O I
10.1111/add.13371
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Genes influence the covariance between conduct disorder (CD) problems and substance use in males, but shared environment is more important in females. We now need to consider: (a) how genetic influences on CD affect correlations across substances from early to later stages of involvement; (b) whether polygenic liability to CD and substance use overlap; (c) environmental pathways of vulnerability (e.g. peers) in females; and (d) sex effects derived from opposite-sex twin pairs.
引用
收藏
页码:1046 / 1047
页数:2
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