Commentary on Verweij et al. (2016): Conduct problems and substance use-genetic and environmental perspectives on sex differences

被引：0

作者：

Few, Lauren R. ^{[1
]}

Agrawal, Arpana ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA

来源：

ADDICTION | 2016年 / 111卷 / 06期

关键词：

Adolescence; cannabis; conduct; correlation; Finntwin; tobacco; twin; GENOME-WIDE ASSOCIATION; BEHAVIORAL DISINHIBITION; ANTISOCIAL-BEHAVIOR; CANNABIS USE; DISORDER; ALCOHOL;

D O I：

10.1111/add.13371

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Genes influence the covariance between conduct disorder (CD) problems and substance use in males, but shared environment is more important in females. We now need to consider: (a) how genetic influences on CD affect correlations across substances from early to later stages of involvement; (b) whether polygenic liability to CD and substance use overlap; (c) environmental pathways of vulnerability (e.g. peers) in females; and (d) sex effects derived from opposite-sex twin pairs.

引用

页码：1046 / 1047

页数：2

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