Effect of Jiaji electroacupuncture in transected rat spinal cord

被引：1

作者：

Teng XiuYing ^{[1
]}

Wang DeSheng ^{[1
]}

Zhang XiaoMei ^{[1
]}

Lai ZengJiao ^{[1
]}

Jiang HaiXia ^{[1
]}

Wu JianLi ^{[1
]}

Qi Huan ^{[1
]}

Yu Qian ^{[1
]}

Yao Shun ^{[1
]}

Song WenBo ^{[1
]}

Yang JingJie ^{[1
]}

Li AiMu ^{[1
]}

机构：

[1] Harbin Med Coll, Affiliated Hosp 1, Harbin 150040, Peoples R China

来源：

CHINESE SCIENCE BULLETIN | 2012年 / 57卷 / 07期

关键词：

Jiaji electroacupuncture; spinal transection; rat; endogenous neural stem cells; NEURAL STEM-CELLS; FUNCTIONAL RECOVERY; DELAYED TREATMENT; INJURY; BRAIN; FIELD;

D O I：

10.1007/s11434-011-4839-7

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We evaluated the effect of Jiaji electroacupuncture on cell proliferation and the expression of markers of endogenous neural stem cell activation after complete spinal cord transection. Female Wistar rats were assigned to 4 groups (n = 24 each): a sham-operated group, a control group, a Jiaji electroacupuncture group, and a Jiaji electroacupuncture preconditioning group. Motor function was significantly improved in the acupuncture groups compared to the control group at 7 and 14 d. Numbers of bromodeoxyuridine (BrdU)-, nestin-, and glial fibrillary acidic protein (GFAP)-positive cells were significantly greater in the acupuncture groups than in the controls at each time point. Expression of nestin and GFAP mRNA was significantly higher in the acupuncture groups than in the controls at each time point. Thus, Jiaji electroacupuncture and preconditioning may promote the proliferation of endogenous neural stem cells after spinal cord transection.

引用

页码：762 / 768

页数：7

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