Recent Advance in Applications of Host-Guest Interaction in Biochemical Analysis

被引：3
作者：
Cui, Lin [1 ]
Zhao, Min-Hui [1 ]
Zhang, Chun-Yang [1 ]
机构：
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Jinan 250014, Peoples R China
来源：
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY | 2020年 / 48卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Host-guest interaction; Biosensors; Biochemical analysis; Sensitive detection; Review; ULTRASENSITIVE ELECTROCHEMICAL IMMUNOASSAY; BETA-CYCLODEXTRIN; SENSING PLATFORM; ELECTROCHEMILUMINESCENCE APTASENSOR; ADENOSINE-TRIPHOSPHATE; RECOGNITION APPROACH; DNA HYBRIDIZATION; IONIC-CONDUCTION; GRAPHENE; NANOPARTICLES;
D O I：
10.19756/j.issn.0253-3820.201090
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Host-guest interaction is the process in which the host selectively combines the guest to form a supramolecular with specific function through non-covalent bonding according to the principles of structural complementarity and energy matching. The identification of biomolecules through antigen-antibody, DNA-protein, enzyme-substrate interactions in biological systems is based on the recognition of non-covalent interactions. The host-guest interaction possesses distinct characteristics of mild reaction conditions and dynamic reversible reaction process , and it not only can efficiently overcome the limitations of covalent bonding, but also can simulate the biological functions at the molecular level. This review summarizes the advance in the applications of host-guest interaction in biochemical analysis including the detection of proteins , nucleic acids , small biological molecules , metal ions and isomers. In addition , the challenges and trends in the development of biosensors based on host-guest interaction are highlighted.
引用
收藏
页码：817 / 826
页数：10
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