Inexpensive Phthalic Acid Promoted Domino Povarov Reaction between Anilines and N-Vinylamides: An Efficient Preparation of Privileged 4-Substituted 2-Methyl-1,2,3,4-tetrahydroquinoline Scaffolds

被引：10
作者：
Kouznetsov, Vladimir V. [1 ]
Merchan Arenas, Diego R. [1 ]
Ortiz Areniz, Cesar J. [1 ]
Melendez Gomez, Carlos M. [2 ]
机构：
[1] Univ Ind Santander, Escuela Quim, Lab Quim Organ & Biomol, Bucaramanga 678, Colombia
[2] Univ Atlantico, Fac Ciencias, Dept Quim, Grp Invest Compuestos Heterocicl, Barranquilla, Colombia
来源：
SYNTHESIS-STUTTGART | 2011年 / 24期
关键词：
2-methyl-1,2,3,4-tetrahydroquinolines; acid-catalyzed Povarov reaction; domino process; phthalic acid; N-vinylamides; DIELS-ALDER REACTION; SOLID-PHASE SYNTHESIS; ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; TETRAHYDROQUINOLINE; PROTOCOL;
D O I：
10.1055/s-0031-1289591
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and simple synthesis of new 2-methyl-1,2,3,4-tetrahydroquinolines with C4 amide fragments based on the phthalic acid promoted domino Povarov reaction between anilines and N-vinylamides has been developed.
引用
收藏
页码：4011 / 4016
页数：6
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