Biomarkers of oral cancer: A current views and directions

被引:4
作者
Doddawad, Vidya Gowdappa [1 ]
Bannimath, Gurupadayya [3 ]
Shivakumar, Shivananda [2 ]
Bannimath, Namitha [4 ]
机构
[1] JSS Acad Higher Educ & Res, JSS Dent Coll & Hosp, Dept Oral Pathol & Microbiol, Mysuru, Karnataka, India
[2] JSS Acad Higher Educ & Res, JSS Dent Coll & Hosp, Dept Oral & Maxillofacial Surg, Mysuru, Karnataka, India
[3] JSS Acad Higher Educ & Res, JSS Coll Pharm, Dept Pharmaceut Chem, Mysuru 570015, Karnataka, India
[4] JSS Acad Higher Educ & Res, JSS Coll Pharm, Dept Pharmacol, Mysuru, Karnataka, India
来源
BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL | 2022年 / 6卷 / 01期
关键词
Head-and-neck cancer; malignancy; oral cancer; tumor markers; TUMOR-MARKERS; CARCINOEMBRYONIC ANTIGEN; ORGANIZER REGIONS; ALPHA-FETOPROTEIN; CLINICAL-PRACTICE; IDENTIFICATION; EXPRESSION; DIAGNOSIS; LESIONS; RELEVANCE;
D O I
10.4103/bbrj.bbrj_204_21
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Tumor biomarkers are the chemical substances that the human body or cancer cells produce in response to the presence of cancer. These markers are mostly proteins that cancer cells produce more quickly. Patients with certain types of cancer have higher levels of these protein substances in their urine, blood, or body tissue and help differentiate between primary and secondary tumors. Oral carcinomas, especially of the head-and-neck region, represent a critical diagnostic challenge not only for the histopathologist but also for the clinician when planning an appropriate treatment protocol. For these reasons, the practice and understanding of these biomarkers have improved tremendously. This review not only sheds light on the different types of tumor markers but also shows their role in some diseases.
引用
收藏
页码:33 / 39
页数:7
相关论文
共 52 条
[1]  
BABU G., 2012, J OROFAC SCI, V4, P87
[2]  
Bancroft JD, 2002, IMMUNOHISTOCHEMISTRY, V5th, P537
[3]   ORAL EXFOLIATIVE CYTOLOGY [J].
BERNSTEIN, ML ;
MILLER, RL .
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 1978, 96 (04) :625-629
[4]  
Bhardwaj J R, 2005, Med J Armed Forces India, V61, P112, DOI 10.1016/S0377-1237(05)80002-4
[5]   K5/K14-positive cells contribute to salivary gland-like breast tumors with myoepithelial differentiation [J].
Boecker, Werner ;
Stenman, Goeran ;
Loening, Thomas ;
Andersson, Mattias K. ;
Bankfalvi, Agnes ;
von Holstein, Sarah ;
Heegaard, Steffen ;
Lange, Alina ;
Berg, Tobias ;
Samoilova, Vera ;
Tiemann, Katharina ;
Buchwalow, Igor .
MODERN PATHOLOGY, 2013, 26 (08) :1086-1100
[6]   Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia [J].
Bragulla, Hermann H. ;
Homberger, Dominique G. .
JOURNAL OF ANATOMY, 2009, 214 (04) :516-559
[7]   Molecular Biomarkers Related to Oral Carcinoma: Clinical Trial Outcome Evaluation in a Literature Review [J].
Cervino, Gabriele ;
Fiorillo, Luca ;
Herford, Alan Scott ;
Romeo, Umberto ;
Bianchi, Alberto ;
Crimi, Salvatore ;
D'Amico, Cesare ;
De Stefano, Rosa ;
Troiano, Giuseppe ;
Santoro, Rossella ;
Laino, Luigi ;
Laino, Gregorio ;
Cicciu, Marco .
DISEASE MARKERS, 2019, 2019
[8]   Contrasting Role of Autophagy in Different Types of Cancer: A Review Toward Biomarkers and Therapeutic Improvement [J].
Chakraborty, Pallab .
BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL, 2021, 5 (03) :260-266
[9]  
Chaudhary M., 2012, J INT DENT, V5, P77
[10]   Tumor markers - A bird's eye view [J].
Daniel, Diana ;
Lalitha, R. M. .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 2016, 28 (06) :475-480