Diagnosis of Food Allergy

被引：38

作者：

Gupta, Malika ^{[1
]}

Cox, Amanda ^{[2
]}

Nowak-Wegrzyn, Anna ^{[2
]}

Wang, Julie ^{[2
]}

机构：

[1] Univ Michigan, Dept Internal Med, Div Allergy & Immunol, 24 Frank Lloyd Wright Dr,Suite H-2100, Ann Arbor, MI 48106 USA

[2] Icahn Sch Med Mt Sinai, Jaffe Food Allergy Inst, Dept Pediat, One Gustave Levy Pl,Box 1198, New York, NY 10029 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2018年 / 38卷 / 01期

关键词：

Diagnosis; Food allergy; Molecular allergen analysis; Serum-specific IgE; Skin prick test; Epitope binding; Basophil activation test; Component-resolved diagnostic testing; COWS MILK; BASOPHIL ACTIVATION; NATURAL-HISTORY; IGE ANTIBODIES; HENS EGG; RECOMBINANT ALLERGENS; HAZELNUT ALLERGY; PEANUT; CHILDREN; CHALLENGE;

D O I：

10.1016/j.iac.2017.09.004

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Food allergy diagnosis remains challenging. Most standard methods are unable to differentiate sensitization from clinical allergy. Recognizing food allergy is of utmost importance to prevent life-threatening reactions. On the other hand, faulty interpretation of tests leads to overdiagnosis and unnecessary food avoidances. Highly predictive models have been established for major food allergens based on skin-prick testing and food specific immunoglobulin E but are lacking for most other foods. Although many newer diagnostic techniques are improving the accuracy of food allergy diagnostics, an oral food challenge remains the only definitive method of confirming a food allergy.

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页码：39 / +

页数：15

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