Autoimmune responses in periodontal diseases

被引：31

作者：

Ali, Javed ^{[1
]}

Pramod, K. ^{[1
]}

Abu Tahir, M. ^{[1
]}

Ansari, S. H. ^{[2
]}

机构：

[1] Fac Pharm, Dept Pharmaceut, New Delhi 110062, India

[2] Fac Pharm, Dept Pharmacognosy & Phytochem, New Delhi 110062, India

来源：

AUTOIMMUNITY REVIEWS | 2011年 / 10卷 / 07期

关键词：

Autoimmunity; Autoimmune responses; Periodontal disease; Gingivitis; Immunopathology; HUMORAL IMMUNE-RESPONSES; KILLER T-CELLS; CREVICULAR FLUID; HOST RESPONSES; YOUNG-ADULTS; SERUM; IMMUNOREGULATION; PATHOGENESIS; MECHANISMS; RELEASE;

D O I：

10.1016/j.autrev.2010.04.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Periodontal diseases are characterized by localized infections and inflammatory conditions and directly affect teeth supporting structures which are the major cause of tooth loss. Several studies have demonstrated the involvement of autoimmune responses in periodontal disease. Evidences of involvement of immunopathology have been reported in periodontal disease. Bacteria in the dental plaque induce antibody formation. Lymphocytes, cytokines and complement system are reported to have an important role in the progression of periodontal disease. The present review describes the involvement of autoimmune responses in periodontal diseases. The mechanisms underlying these responses are also discussed. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：426 / 431

页数：6

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