Palladium-Catalyzed Three-Component Reaction of 2,3-Allenyl Amines, Isocyanates, and Organic Halides: A Diversified Assembly of Imidazolidinones

被引：15

作者：

Shu, Wei ^{[3
]}

Yu, Qiong ^{[2
]}

Jia, Guochen ^{[1
]}

Ma, Shengming ^{[2
,3
]}

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

[2] E China Normal Univ, Dept Chem, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 17期

基金：

中国国家自然科学基金;

关键词：

allenes; amines; cyclization; heterocycles; isocyanates; palladium; CGRP RECEPTOR ANTAGONISTS; CYCLIC UREA DERIVATIVES; MULTICOMPONENT REACTIONS; STEREOSELECTIVE SYNTHESIS; 2+2+2 CYCLOADDITION; EFFICIENT SYNTHESIS; INSERTION REACTIONS; HETEROCYCLES; INHIBITORS; IMIDAZOLONES;

D O I：

10.1002/chem.201003611

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A three-component reaction of 2,3-allenyl amines with isocyanates and organic halides has been developed. Two carbon-nitrogen bonds as well as a carbon-carbon bond were sequentially formed to construct imidazolidinone derivatives in good to excellent yields (see scheme). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4720 / 4723

页数：4

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