A novel "on-off-on" fluorescent sensor for 6-thioguanine and Hg2+ based on g-C3N4 nanosheets

被引：54

作者：

Duan, Junling ^{[1
]}

Zhang, Yuanhong ^{[1
]}

Yin, Yanbin ^{[1
]}

Li, Houshen ^{[1
]}

Wang, Jun ^{[2
]}

Zhu, Lusheng ^{[2
]}

机构：

[1] Shandong Agr Univ, Coll Chem & Mat Sci, Tai An 271018, Shandong, Peoples R China

[2] Shandong Agr Univ, Coll Resources & Environm, Tai An 271018, Shandong, Peoples R China

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2018年 / 257卷

基金：

中国国家自然科学基金;

关键词：

g-C3N4; nanosheets; Fluorescence; Sensor; 6-Thioguanine; Mercury; GRAPHITIC CARBON NITRIDE; QUANTUM DOTS; AQUEOUS-SOLUTION; LYMPHOBLASTIC-LEUKEMIA; SELECTIVE DETECTION; GOLD NANOPARTICLES; GREEN SYNTHESIS; CU2+; 6-MERCAPTOPURINE; MERCURY;

D O I：

10.1016/j.snb.2017.10.071

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A facile fluorescence "on-off-on" approach for sensing 6-Thioguanine (6-TG) and Hg2+ was designed based on g-C3N4 nanosheets. It was found that in the absence of Hg2+, the addition of 6-TG to g-C3N4 nanosheets solution resulted in the fluorescence quenching of g-C3N4 nanosheets (turn off). However, in the presence of Hg2+, the quenched fluorescence of g-C3N4 nanosheets was recovered ( turn on), because the high affinity of Hg2+ and 6-TG resulted in the loss of molecular interactions between 6-TG and g-C3N4 nanosheets. The quantitative detection of 6-TG was obtained via the fluorescence quenching of g-C3N4 nanosheets with a detection limit of 65 nM. Meantime, the 6-TG-g-C3N4 nanosheets system could be used as a fluorescent "turn on" sensor for Hg2+. The detection limit for Hg2+ was 37 nM. The proposed method showed high selectivity for the detection of 6-TG and Hg2+. In addition, it was successfully applied to detect Hg2+ in real water samples. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：504 / 510

页数：7

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