Palladium-catalyzed chloroimination of imidoyl chlorides to a triple bond: An intramolecular reaction leading to 4-chloroquinolines

被引：48
|
作者：
Isobe, Akira [1 ]
Takagi, Jun [1 ]
Katagiri, Toshimasa [1 ]
Uneyama, Kenji [1 ]
机构：
[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7008530, Japan
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 13期
关键词：
D O I：
10.1021/ol800512m
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this paper, a new type of effective chloroimination was reported. This reaction afforded 4-chloro-2-perfluoroalkyl quinolines from fluorinated imidoyl chlorides in high yields. This is the first achievement of oxidative addition-reductive elimination type C-Cl bond activation by chloropalladation.
引用
收藏
页码：2657 / 2659
页数：3
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