An antitumor compound julibroside J28 from Albizia julibrissin

被引：58

作者：

Liang, H

Tong, WY

Zhao, YY ^{[1
]}

Cui, JR

Tu, GZ

机构：

[1] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100083, Peoples R China

[2] Peking Univ, Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

[3] Beijing INst Microchem, Beijing 100091, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 20期

基金：

中国国家自然科学基金;

关键词：

Albizia julibrissin; julibroside J(28); antitumor activity;

D O I：

10.1016/j.bmcl.2005.07.015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new triterpenoid saponin, julibroside J(28) (1), was isolated from the stem bark of Albizia julibrissin Durazz (Legurilinosae) by using chromatographic method. The structure of 1 was established by spectroscopic methods. I displayed significant antitumor activity in vitro against PC-3M-1E8, Bel-7402, and HeLa cancer cell lines at 10 mu M assayed by SRB method. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4493 / 4495

页数：3

共 5 条

[1] Three new triterpenoidal saponins acylated with monoterpenic acid from albizziae cortex [J].