MERS, SARS and other coronaviruses as causes of pneumonia

被引:664
作者
Yin, Yudong [1 ]
Wunderink, Richard G. [2 ]
机构
[1] Capital Med Univ, Beijing Chao Yang Hosp, Dept Infect Dis & Clin Microbiol, Beijing, Peoples R China
[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Pulm & Crit Care, 676 North St Clair St,Arkes 14-015, Chicago, IL 60611 USA
关键词
human coronaviruses; Middle East respiratory syndrome; pneumonia; severe acute respiratory syndrome; EAST RESPIRATORY SYNDROME; ANGIOTENSIN-CONVERTING ENZYME-2; INTERFERON-BETA; SAUDI-ARABIA; VIRAL LOAD; ACE2; INFECTION; RECEPTOR; OUTCOMES; BETACORONAVIRUS;
D O I
10.1111/resp.13196
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Human coronaviruses (HCoVs) have been considered to be relatively harmless respiratory pathogens in the past. However, after the outbreak of the severe acute respiratory syndrome (SARS) and emergence of the Middle East respiratory syndrome (MERS), HCoVs have received worldwide attention as important pathogens in respiratory tract infection. This review focuses on the epidemiology, pathogenesis and clinical characteristics among SARS-coronaviruses (CoV), MERS-CoV and other HCoV infections.
引用
收藏
页码:130 / 137
页数:8
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