Modeling the dynamics of HIV-1 and CD4 and CD8 lymphocytes

被引：24
|
作者：
de Souza, FMC
de Mendonca, RN
机构：
[1] Rua Neto de Mendonca, 121, Tamarineira, CEP 52 050-100
来源：
IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE | 1999年 / 18卷 / 01期
关键词：
D O I：
10.1109/51.740960
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A mathematical model was developed to explain the interaction between human immunodeficiency virus (HIV) and the immune system. The model can be used to gain a better understanding of the dynamical aspects of HIV. Particular focus is given to the role of CD4 and CD8 lymphocyte cells in curbing the virus growth rate.
引用
收藏
页码：21 / 24
页数：4
相关论文
共 50 条
  • [31] The dynamic association between Frailty, CD4 and CD4/CD8 ratio in people aging with HIV
    Guaraldi, Giovanni
    Zona, Stefano
    Silva, Ana Rita
    Menozzi, Marianna
    Dolci, Giovanni
    Milic, Jovana
    Carli, Federica
    Mussini, Cristina
    PLOS ONE, 2019, 14 (02):
  • [32] ROLES OF CD3, CD4 AND CD8 IN SYNOVIAL LYMPHOCYTES OF RHEUMATOID ARTHRITIS
    Xiong, Guangyi
    Lei, Ting
    Dong, Shuhui
    Xu, Lina
    LI, Mingshan
    Wang, Ruilin
    POLISH JOURNAL OF PATHOLOGY, 2022, 73 (01) : 21 - 26
  • [33] Fas ligand-mediated depletion of CD4 and CD8 lymphocytes by monomeric HIV-1-gp120
    Uchiyama, J
    Kishi, S
    Yagita, H
    Matsuzaki, S
    Koga, Y
    ARCHIVES OF VIROLOGY, 1997, 142 (09) : 1771 - 1785
  • [34] Mitochondrial DNA content in CD4 and CD8 peripheral blood lymphocytes of HIV+ patients with lipodystrophy
    Cossarizza, A
    Riva, A
    Pinti, M
    Ammannato, S
    Fedeli, P
    Mussini, C
    Esposito, R
    Galli, M
    ANTIVIRAL THERAPY, 2002, 7 (03) : L44 - L44
  • [35] EFFECT OF CYTOKINES ON HIV REPLICATION IN CD4(+) LYMPHOCYTES - LACK OF IDENTITY WITH THE CD8(+) CELL ANTIVIRAL FACTOR
    MACKEWICZ, CE
    ORTEGA, H
    LEVY, JA
    CELLULAR IMMUNOLOGY, 1994, 153 (02) : 329 - 343
  • [36] A STRUCTURAL VIEW OF CD4 AND CD8
    LEAHY, DJ
    FASEB JOURNAL, 1995, 9 (01): : 17 - 25
  • [37] THE STRUCTURE OF THE CD4 AND CD8 GENES
    LITTMAN, DR
    ANNUAL REVIEW OF IMMUNOLOGY, 1987, 5 : 561 - 584
  • [38] CYTOTOXIC T-LYMPHOCYTES THAT KILL AUTOLOGOUS CD4(+) LYMPHOCYTES ARE ASSOCIATED WITH CD4(+) LYMPHOCYTE DEPLETION IN HIV-1 INFECTION
    GRANT, MD
    SMAIL, FM
    ROSENTHAL, KL
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1994, 7 (06): : 571 - 579
  • [39] Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers
    Chereau, Fanny
    Madec, Yoann
    Sabina, Caroline
    Obel, Niels
    Ruiz-Mateos, Ezequiel
    Chrysos, Georgios
    Fidler, Sarah
    Lehmann, Clara
    Zangerle, Robert
    Wittkop, Linda
    Reiss, Peter
    Hamouda, Osamah
    Estrada Perez, Vicente
    Leal, Manuel
    Mocroft, Amanda
    Garcia De Olalla, Patricia
    Ammassari, Adriana
    Monforte, Antonella D'Arminio
    Mussini, Cristina
    Segura, Ferran
    Castagna, Antonella
    Cavassini, Matthias
    Grabar, Sophie
    Morlat, Philippe
    De Wit, Stephane
    Lambotte, Olivier
    Meyer, Laurence
    PLOS ONE, 2017, 12 (04):
  • [40] Establishment of Normal Reference Intervals for CD3(+), CD4(+), CD8(+), and CD4(+) to CD8(+) Ratio of T Lymphocytes in HIV Negative Adults from University of Gondar Hospital, North West Ethiopia
    Gize, Addisu
    Mathewos, Biniam
    Moges, Beyene
    Workineh, Meseret
    Gedefaw, Lealem
    AIDS RESEARCH AND TREATMENT, 2014, 2014
12345