Storage of equine red blood cells as a concentrate

被引:21
|
作者
Niinisto, Kati [1 ]
Raekallio, Marja [1 ]
Sankari, Satu [1 ]
机构
[1] Univ Helsinki, Dept Equine & Small Anim Med, Fac Vet Med, FIN-00014 Helsinki, Finland
来源
VETERINARY JOURNAL | 2008年 / 176卷 / 02期
关键词
horse; erythrocyte; transfusion; haemolysis; potassium;
D O I
10.1016/j.tvjl.2007.02.015
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The study was undertaken to determine how equine red blood cells (RBCs) survive in storage bags designed for use with human RBCs. Separated RBCs were stored in a routine manner for 35 days and examined every 7 days for storage lesions. Measured parameters included haematology, haemolysis, pH, potassium, lactate, adenosine triphosphate (ATP) and 2,3-diphosphoglycerate (2,3-DPG). All tests were performed in vitro. Haematology did not change significantly. Haemolysis increased during storage but did not exceed human limits. pH and 2,3-DPG decreased, while lactate, potassium and ATP increased. RBCs deteriorated somewhat during storage, but when compared with human in vitro parameters, remained suitable for transfusion. It is concluded that equine erythrocytes can be stored for at least 35 days before transfusion. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:227 / 231
页数:5
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