Total Synthesis of (+)-Tabertinggine

被引:8
作者
Dan, Long [1 ]
Liu, Zhiqiang [1 ]
Huo, Liang [1 ]
Yang, Hesi [1 ]
Yi, Jiuzhou [1 ]
Xie, Xingang [1 ]
She, Xuegong [1 ]
机构
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
基金
中国国家自然科学基金;
关键词
Chiral pool; Pictet-spengler reaction; Total synthesis; PICTET-SPENGLER REACTIONS; INDOLE ALKALOIDS; GENERAL-APPROACH; IBOGA; DECARBOXYLATION; CYCLIZATION; ACIDS;
D O I
10.1016/j.tet.2022.132781
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A concise total synthesis of (+)-tabertinggine was accomplished in 12 steps with 6.1% overall yield enabled by a Pictet-Spengler condensation/lactamization cascade reaction. (C) 2022 Elsevier Ltd. All rights reserved.
引用
收藏
页数:5
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