Palladium-catalyzed allylic alkylation of tert-butyl(diphylmethylene)-glycinate with simple allyl esters under chiral phase transfer conditions

被引：164

作者：

Chen, GS

Deng, YJ ^{[1
]}

Gong, LZ

Mi, AQ

Cui, X

Jiang, YZ

Choi, MCK

Chan, ASC

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China

[2] Hong Kong Polytech Univ, Open Lab Chriotechnol, Hong Kong, Hong Kong, Peoples R China

[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 11期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0957-4166(01)00276-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The first example of palladium-catalyzed allylic alkylation of,in imino ester with simple allyl esters in the presence of a chiral quaternary ammonium salt is reported. The presence of molecular sieves was found to have a beneficial effect on the enantioselectivity of the reaction by scavenging water from the system. Alkylated products vith e.e.s of up to 61% were obtained. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：1567 / 1571

页数：5

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