Neuropharmacological profile of ethnomedicinal plants of Guatemala

被引：21

作者：

Cifuentes, CM ^{[1
]}

Gómez-Serranillos, MP ^{[1
]}

Iglesias, I ^{[1
]}

del Fresno, AMV ^{[1
]}

机构：

[1] Univ Complutense Madrid, Fac Farm, Dept Farmacol, E-28040 Madrid, Spain

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 76卷 / 03期

关键词：

ethnomedicinal plants; Guatemala; CNS activity;

D O I：

10.1016/S0378-8741(01)00235-5

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

We carried out the Irwin's test with some different extracts of the aerial parts of Thidax procumbens L., the leaves of Neurolaena lobata (L.) R. Br., bark and leaves of Byrsonima crassifolia (L.) Kunth. and Gliricidia sepium Jacq. Walp., and root and leaves of Petiveria alliacea L. At dosage of 1.25 g dried plant/kg weight aqueous extracts of bark and leaves of Byrsonima crassifolia (L.) Kunth. and Gliricidia sepium Jacq. Walp. demonstrated the most activity: decrease in motor activity, back tonus, reversible parpebral ptosis, catalepsy and strong hypothermia. These extracts of both plants were assayed for effects on CNS and they caused very significant reductions in spontaneous locomotor activity, exploratory behavior and rectal temperature and they increased the sodium pentobarbital-induced sleeping time. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：223 / 228

页数：6

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