Synthesis and evaluation of cytotoxic activity of novel arylsulfonylimidazolidinones

被引：33

作者：

Jung, SH ^{[1
]}

Song, JS ^{[1
]}

Lee, HS ^{[1
]}

Choi, SU ^{[1
]}

Lee, CO ^{[1
]}

机构：

[1] KOREA RES INST CHEM TECHNOL,TAEJON 305343,SOUTH KOREA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 21期

关键词：

D O I：

10.1016/0960-894X(96)00463-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthesis of novel arylsulfonylimidazolidinones 3 and 4 containing sulfonylurea pharmacophore and evaluation of their in vitro cytotoxicity against human cell lines were investigated. As a result, a series of 4-phenyl-1(N)-arylsulfonylimidazolidinones have been found to be the potential anticancer agent. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2553 / 2558

页数：6

共 19 条

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