In vitro synergy testing of anidulafungin with itraconazole, voriconazole, and amphotericin B against Aspergillus spp. and Fusatium spp.

被引:64
作者
Philip, A [1 ]
Odabasi, Z [1 ]
Rodriguez, J [1 ]
Paetznick, VL [1 ]
Chen, E [1 ]
Rex, JH [1 ]
Ostrosky-Zeichner, L [1 ]
机构
[1] Univ Texas, Sch Med, Div Infect Dis, Lab Mycol Res, Houston, TX 77030 USA
关键词
D O I
10.1128/AAC.49.8.3572-3574.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The in vitro interactions of anidulafungin with itraconazole, voriconazole, and amphotericin B were evaluated by using the checkerboard method. For Aspergillus spp., anidulafungin with amphotericin B showed indifference for 16/26 isolates, while anidulafungin with either azole showed a synergy trend for 18/26 isolates. All drug combinations showed indifference for 7/7 Fusarium sp. isolates.
引用
收藏
页码:3572 / 3574
页数:3
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