Lymphocyte migration into tissue: The paradigm derived from CD4 subsets

被引：84
作者：
Bradley, LM [1 ]
Watson, SR [1 ]
机构：
[1] UNIV CALIF SAN DIEGO,CTR CANC,LA JOLLA,CA 92093
来源：
CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 03期
关键词：
D O I：
10.1016/S0952-7915(96)80118-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The appropriate recirculation and migration of naive, effector and memory T cells into inflamed tissue are precisely controlled by adhesive interactions with vascular endothelium. Analyses of CD4 lymphocytes have indicated that naive and antigen-experienced cells exhibit distinctive patterns of homing and recirculation, and that subsets of cells preferentially localize in different anatomical locations as a consequence of previous antigen exposure and differences in adhesion receptor usage.
引用
收藏
页码：312 / 320
页数：9
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