Thyrotoxic periodic paralysis induced by pulse methylprednisolone

被引：21

作者：

Wongraoprasert, Somporn ^{[1
]}

Buranasupkajorn, Patinut ^{[1
]}

Sridama, Vitaya ^{[1
]}

Snabboon, Thiti ^{[1
]}

机构：

[1] Chulalongkorn Univ, Fac Med, Dept Internal Med, Div Endocrine & Metab, Bangkok 10330, Thailand

来源：

INTERNAL MEDICINE | 2007年 / 46卷 / 17期

关键词：

hypokalemia; thyroid periodic paralysis; steroid;

D O I：

10.2169/internalmedicine.46.0044

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a young Thai man who developed acute flaccid paralysis after receiving pulse methylprednisolone for chronic inflammatory demyelinating polyneuropathy. Hypokalemia from intracellular shift was confirmed by calculation of transtubular potassium gradient (TTKG). His muscle strength and serum potassium fully recovered with a small amount of potassium replacement. Graves' disease was subsequently diagnosed and treated with radioactive iodine. We suggest that acute paralysis after the use of steroids should raise a suspicion of thyrotoxic periodic paralysis (TPP). The potential mechanisms of steroid-induced TPP are discussed.

引用

页码：1431 / 1433

页数：3

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