A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways

被引：352

作者：

Maniatis, T ^{[1
]}

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

来源：

GENES & DEVELOPMENT | 1999年 / 13卷 / 05期

关键词：

D O I：

10.1101/gad.13.5.505

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：505 / 510

页数：6

共 38 条

[21] Proteolysis and the G1-S transition:: the SCF connection [J].

Krek, W .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1998, 8 (01) :36-42

[22] Signal transduction - Catalysis by a multiprotein I kappa B kinase complex [J].

Maniatis, T .

SCIENCE, 1997, 278 (5339) :818-819

[23] A novel human WD protein, h-βTrCP, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif [J].

Margottin, F ;

Bour, SP ;

Durand, H ;

Selig, L ;

Benichou, S ;

Richard, V ;

Thomas, D ;

Strebel, K ;

Benarous, R .

MOLECULAR CELL, 1998, 1 (04) :565-574

[24] β-TrCP is a negative regulator of the Wnt/β-catenin signaling pathway and dorsal axis formation in Xenopus embryos [J].

Marikawa, Y ;

Elinson, RP .

MECHANISMS OF DEVELOPMENT, 1998, 77 (01) :75-80

[25]

Morisato D, 1995, ANNU REV GENET, V29, P371, DOI 10.1146/annurev.genet.29.1.371

[26] Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator [J].

Ohlmeyer, JT ;

Kalderon, D .

NATURE, 1998, 396 (6713) :749-753

[27] Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin [J].

Orford, K ;

Crockett, C ;

Jensen, JP ;

Weissman, AM ;

Byers, SW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (40) :24735-24738

[28] THE UBIQUITIN-PROTEASOME PATHWAY IS REQUIRED FOR PROCESSING THE NF-KAPPA-B1 PRECURSOR PROTEIN AND THE ACTIVATION OF NF-KAPPA-B [J].

PALOMBELLA, VJ ;

RANDO, OJ ;

GOLDBERG, AL ;

MANIATIS, T .

CELL, 1994, 78 (05) :773-785

[29] Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis [J].

Patton, EE ;

Willems, AR ;

Tyers, M .

TRENDS IN GENETICS, 1998, 14 (06) :236-243

[30]

PETERS JM, 1998, UBIQUITIN BIOL CELL

← 1 2 3 4 →