Production of alginate by Azotobacter vinelandii in a stirred fermentor simulating the evolution of power input observed in shake flasks

被引:22
作者
Pena, C. [1 ]
Millan, M. [1 ]
Galindo, E. [1 ]
机构
[1] Univ Nacl Autonoma Mexico, Inst Biotechnol, Dept Ingn Celular & Biocatalisis, Morelos 62250, Mexico
关键词
alginate; molecular mass; power input; scaling-up;
D O I
10.1016/j.procbio.2008.02.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
By simulating the evolution of the actual power input observed in shake flasks it was possible to produce, in a fermentor, alginates having a very similar mean molecular mass (1700 kDa) to that obtained in the cultures developed in shake flasks (1800 kDa). Similar profiles of dissolved oxygen tension and oxygen transfer rate could be the reason. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:775 / 778
页数:4
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