Coronary Arterial Function and Disease in Women With No Obstructive Coronary Arteries

被引:40
作者
Reynolds, Harmony R. [2 ]
Merz, C. Noel Bairey [1 ]
Berry, Colin [3 ,4 ,5 ]
Samuel, Rohit [6 ]
Saw, Jacqueline [6 ]
Smilowitz, Nathaniel R. [2 ]
de Souza, Ana Carolina do A. H. [7 ,8 ,9 ]
Sykes, Robert [4 ]
Taqueti, Viviany R. [7 ,8 ,9 ]
Wei, Janet [1 ]
机构
[1] Cedars Sinai Med Ctr, Smidt Heart Inst, Barbra Streisand Womens Heart Ctr, 127 S San Vicente Blvd A3212, Los Angeles, CA 90048 USA
[2] New York Univ Grossman Sch Med, Sarah Ross Soter Ctr Womens Cardiovasc Res, Dept Med, Leon H Charney Div Cardiol, New York, NY USA
[3] Univ Glasgow, British Heart Fdn Glasgow Cardiovasc Res Ctr, Glasgow, Lanark, Scotland
[4] Golden Jubilee Natl Hosp, West Scotland Heart & Lung Ctr, Glasgow, Lanark, Scotland
[5] Queen Elizabeth Univ Hosp, NHS Greater Glasgow & Clyde Hlth Board, Dept Cardiol, Glasgow, Lanark, Scotland
[6] Univ British Columbia, Vancouver Gen Hosp, Vancouver, BC, Canada
[7] Harvard Med Sch, Dept Radiol, Cardiovasc Imaging Program, Boston, MA 02115 USA
[8] Harvard Med Sch, Dept Med Cardiol, Cardiovasc Imaging Program, Boston, MA 02115 USA
[9] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA
基金
英国医学研究理事会;
关键词
coronary disease; coronary vessels; myocardial infarction; risk factors; sex characteristics; ACUTE MYOCARDIAL-INFARCTION; ISCHEMIC-HEART-DISEASE; SEX-RELATED DIFFERENCES; LONG-TERM PROGNOSIS; COMPUTED-TOMOGRAPHY ANGIOGRAPHY; POSITRON-EMISSION-TOMOGRAPHY; BYPASS GRAFT-SURGERY; MICROVASCULAR DYSFUNCTION; FLOW RESERVE; GENDER-DIFFERENCES;
D O I
10.1161/CIRCRESAHA.121.319892
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ischemic heart disease (IHD) is the leading cause of mortality in women. While traditional cardiovascular risk factors play an important role in the development of IHD in women, women may experience sex-specific IHD risk factors and pathophysiology, and thus female-specific risk stratification is needed for IHD prevention, diagnosis, and treatment. Emerging data from the past 2 decades have significantly improved the understanding of IHD in women, including mechanisms of ischemia with no obstructive coronary arteries and myocardial infarction with no obstructive coronary arteries. Despite this progress, sex differences in IHD outcomes persist, particularly in young women. This review highlights the contemporary understanding of coronary arterial function and disease in women with no obstructive coronary arteries, including coronary anatomy and physiology, mechanisms of ischemia with no obstructive coronary arteries and myocardial infarction with no obstructive coronary arteries, noninvasive and invasive diagnostic strategies, and management of IHD.
引用
收藏
页码:529 / 551
页数:23
相关论文
共 204 条
  • [41] 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons
    Fihn, Stephan D.
    Gardin, Julius M.
    Abrams, Jonathan
    Berra, Kathleen
    Blankenship, James C.
    Dallas, Apostolos P.
    Douglas, Pamela S.
    Foody, JoAnne M.
    Gerber, Thomas C.
    Hinderliter, Alan L.
    King, Spencer B., III
    Kligfield, Paul D.
    Krumholz, Harlan M.
    Kwong, Raymond Y. K.
    Lim, Michael J.
    Linderbaum, Jane A.
    Mack, Michael J.
    Munger, Mark A.
    Prager, Richard L.
    Sabik, Joseph F.
    Shaw, Leslee J.
    Sikkema, Joanna D.
    Smith, Craig R., Jr.
    Smith, Sidney C.
    Spertus, John A.
    Williams, Sankey V.
    [J]. CIRCULATION, 2012, 126 (25) : E354 - U191
  • [42] Ischemia and No Obstructive Coronary Artery Disease Prevalence and Correlates of Coronary Vasomotion Disorders
    Ford, Thomas J.
    Yii, Eric
    Sidik, Novalia
    Good, Richard
    Rocchiccioli, Paul
    McEntegart, Margaret
    Watkins, Stuart
    Eteiba, Hany
    Shaukat, Aadil
    Lindsay, Mitchell
    Robertson, Keith
    Hood, Stuart
    McGeoch, Ross
    McDade, Robert
    McCartney, Peter
    Corcoran, David
    Collison, Damien
    Rush, Christopher
    Stanley, Bethany
    McConnachie, Alex
    Sattar, Naveed
    Touyz, Rhian M.
    Oldroyd, Keith G.
    Berry, Colin
    [J]. CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2019, 12 (12)
  • [43] 1-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CorMicA)
    Ford, Thomas J.
    Stanley, Bethany
    Sidik, Novalia
    Good, Richard
    Rocchiccioli, Paul
    McEntegart, Margaret
    Watkins, Stuart
    Eteiba, Hany
    Shaukat, Aadil
    Lindsay, Mitchell
    Robertson, Keith
    Hood, Stuart
    McGeoch, Ross
    McDade, Robert
    Yii, Eric
    McCartney, Peter
    Corcoran, David
    Collison, Damien
    Rush, Christopher
    Sattar, Naveed
    McConnachie, Alex
    Touyz, Rhian M.
    Oldroyd, Keith G.
    Berry, Colin
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2020, 13 (01) : 33 - 45
  • [44] Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina The CorMicA Trial
    Ford, Thomas J.
    Stanley, Bethany
    Good, Richard
    Rocchiccioli, Paul
    McEntegart, Margaret
    Watkins, Stuart
    Eteiba, Hany
    Shaukat, Aadil
    Lindsay, Mitchell
    Robertson, Keith
    Hood, Stuart
    McGeoch, Ross
    McDade, Robert
    Yii, Eric
    Sidik, Novalia
    McCartney, Peter
    Corcoran, David
    Collison, Damien
    Rush, Christopher
    McConnachie, Alex
    Touyz, Rhian M.
    Oldroyd, Keith G.
    Berry, Colin
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 72 (23) : 2841 - 2855
  • [45] Prediction of Short-Term Cardiovascular Events Using Quantification of Global Myocardial Flow Reserve in Patients Referred for Clinical 82Rb PET Perfusion Imaging
    Fukushima, Kenji
    Javadi, Mehrbod S.
    Higuchi, Takahiro
    Lautamaeki, Riikka
    Merrill, Jennifer
    Nekolla, Stephan G.
    Bengel, Frank M.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2011, 52 (05) : 726 - 732
  • [46] Relationship between FFR, CFR and coronary microvascular resistance - Practical implications for FFR-guided percutaneous coronary intervention
    Garcia, Damien
    Harbaoui, Brahim
    van de Hoef, Tim P.
    Meuwissen, Martijn
    Nijjer, Sukhjinder S.
    Echavarria-Pinto, Mauro
    Davies, Justin E.
    Piek, Jan J.
    Lantelme, Pierre
    [J]. PLOS ONE, 2019, 14 (01):
  • [47] OCT and CMR for the Diagnosis of Patients Presenting With MINOCA and Suspected Epicardial Causes
    Gerbaud, Edouard
    Arabucki, Fabien
    Nivet, Hubert
    Barbey, Christophe
    Cetran, Laura
    Chassaing, Stephan
    Seguy, Benjamin
    Lesimple, Arnaud
    Cochet, Hubert
    Montaudon, Michel
    Laurent, Francois
    Bar, Olivier
    Tearney, Guillermo J.
    Coste, Pierre
    [J]. JACC-CARDIOVASCULAR IMAGING, 2020, 13 (12) : 2619 - 2631
  • [48] International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology
    Ghadri, Jelena-Rima
    Wittstein, Ilan Shor
    Prasad, Abhiram
    Sharkey, Scott
    Dote, Keigo
    Akashi, Yoshihiro John
    Cammann, Victoria Lucia
    Crea, Filippo
    Galiuto, Leonarda
    Desmet, Walter
    Yoshida, Tetsuro
    Manfredini, Roberto
    Eitel, Ingo
    Kosuge, Masami
    Nef, Holger M.
    Deshmukh, Abhishek
    Lerman, Amir
    Bossone, Eduardo
    Citro, Rodolfo
    Ueyama, Takashi
    Corrado, Domenico
    Kurisu, Satoshi
    Ruschitzka, Frank
    Winchester, David
    Lyon, Alexander R.
    Omerovic, Elmir
    Bax, Jeroen J.
    Meimoun, Patrick
    Tarantini, Guiseppe
    Rihal, Charanjit
    Y-Hassan, Shams
    Migliore, Federico
    Horowitz, John D.
    Shimokawa, Hiroaki
    Luescher, Thomas Felix
    Templin, Christian
    [J]. EUROPEAN HEART JOURNAL, 2018, 39 (22) : 2032 - 2046
  • [49] Anatomic Versus Physiologic Assessment of Coronary Artery Disease
    Gould, K. Lance
    Johnson, Nils P.
    Bateman, Timothy M.
    Beanlands, Rob S.
    Bengel, Frank M.
    Bober, Robert
    Camici, Paolo G.
    Cerqueira, Manuel D.
    Chow, Benjamin J. W.
    Di Carli, Marcelo F.
    Dorbala, Sharmila
    Gewirtz, Henry
    Gropler, Robert J.
    Kaufmann, Philipp A.
    Knaapen, Paul
    Knuuti, Juhani
    Merhige, Michael E.
    Rentrop, K. Peter
    Ruddy, Terrence D.
    Schelbert, Heinrich R.
    Schindler, Thomas H.
    Schwaiger, Markus
    Sdringola, Stefano
    Vitarello, John
    Williams, Kim A.
    Gordon, Donald
    Dilsizian, Vasken
    Narula, Jagat
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (18) : 1639 - 1653
  • [50] Does Coronary Flow Trump Coronary Anatomy?
    Gould, K. Lance
    [J]. JACC-CARDIOVASCULAR IMAGING, 2009, 2 (08) : 1009 - 1023