Effect of vaginal probiotic lactobacilli on in vitro-induced sperm lipid peroxidation and its impact on sperm motility and viability

被引：64

作者：

Barbonetti, Arcangelo ^{[1
,2
]}

Cinque, Benedetta ^{[3
]}

Vassallo, Maria Rosaria Caterina ^{[1
]}

Mineo, Salvatore ^{[1
]}

Francavilla, Sandro ^{[1
]}

Cifone, Maria Grazia ^{[3
]}

Francavilla, Felice ^{[1
]}

机构：

[1] Univ Aquila, Dept Internal Med, Androl Unit, I-67100 Laquila, Italy

[2] San Raffaele Sulmona, Clin Res Ctr, Sulmona, Italy

[3] Univ Aquila, Dept Expt Med, I-67100 Laquila, Italy

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 08期

关键词：

Probiotic lactobacilli; bacterial vaginosis; human spermatozoa; lipid peroxidation; sperm motility; BACTERIAL VAGINOSIS; WOMEN;

D O I：

10.1016/j.fertnstert.2011.03.066

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A combination of three selected strains of lactobacilli (Lactobacillus brevis [CD2], L. salivarius [FV2], and L. plantarum [FV9]), whose effectiveness in treating bacterial vaginosis in the form of vaginal tablets has been reported recently, prevented sperm lipid peroxidation that was induced in vitro by a ferrous ion promoter, thus preserving sperm motility and viability. This finding suggests the potential of vaginal probiotic lactobacilli for protecting human spermatozoa from radical oxygen species in the presence of vaginal disorders, thereby improving the fertilization potential of the female host. (Fertil Steril (R) 2011; 95: 2485-8. (C) 2011 by American Society for Reproductive Medicine.)

引用

页码：2485 / 2488

页数：4

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