Mental retardation - An overview

被引：0
|
作者：
Holinski-Feder, E. [1 ]
机构：
[1] Med Genet Zentrum Munchen, D-80335 Munich, Germany
来源：
MONATSSCHRIFT KINDERHEILKUNDE | 2008年 / 156卷 / 04期
关键词：
mental retardation; genetics; syndromology; differential diagnosis; clarification;
D O I：
10.1007/s00112-008-1682-2
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Mental retardation is defined as an IQ < 70, and affects approximately 2% of the general population. Between 40% and 50% of these patients have a genetic defect. While databases currently list 1600 genetic syndromes with mental retardation, the number of defects without specific syndromology is assumed to be much higher. This article aims to present the differential diagnosis of the more frequent genetic syndromes and help with the clarification of syndromologic and non-syndromoligic forms.
引用
收藏
页码：337 / +
页数：10
相关论文
共 50 条
  • [31] Metabolic disorders and mental retardation
    Kahler, SG
    Fahey, MC
    AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS, 2003, 117C (01) : 31 - 41
  • [32] Genetics and pathophysiology of mental retardation
    Jamel Chelly
    Malik Khelfaoui
    Fiona Francis
    Beldjord Chérif
    Thierry Bienvenu
    European Journal of Human Genetics, 2006, 14 : 701 - 713
  • [33] Balanced translocations in mental retardation
    Geert Vandeweyer
    R. Frank Kooy
    Human Genetics, 2009, 126 : 133 - 147
  • [34] Pharmacotherapy of disorders in mental retardation
    Aman, MG
    Collier-Crespin, A
    Lindsay, RL
    EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2000, 9 : 98 - 107
  • [35] Chromosomal abnormalities in mental retardation
    Sireteanu, Adriana
    Rusu, Cristina
    Volosciuc, Mihail
    Butnariu, Lacramioara
    Braha, Elena Emanuela
    Panzaru, Monica
    Popescu, Roxana
    Bujoran, Cornel
    Gramescu, Mihaela
    Ivanov, Luliu
    Caba, Lavinia
    Covic, Mircea
    Gorduza, Eusebiu Vlad
    CHROMOSOME RESEARCH, 2011, 19 : S111 - S112
  • [36] Sexuality and youngsters with mental retardation
    Waldman, HB
    Swerdloff, M
    Perlman, SP
    JOURNAL OF DENTISTRY FOR CHILDREN, 1999, 66 (05): : 348 - +
  • [37] MRI in children with mental retardation
    Soto-Ares, G
    Joyes, B
    Lemaître, MP
    Vallée, L
    Pruvo, JP
    PEDIATRIC RADIOLOGY, 2003, 33 (05) : 334 - 345
  • [38] MRI in children with mental retardation
    Gustavo Soto-Ares
    Béatrice Joyes
    Marie-Pierre Lemaître
    Louis Vallée
    Jean-Pierre Pruvo
    Pediatric Radiology, 2003, 33 : 334 - 345
  • [39] ECT in mental retardation: A review
    van Waarde, JA
    Stolker, JJ
    van der Mast, RC
    JOURNAL OF ECT, 2001, 17 (04) : 236 - 243
  • [40] Genetic syndromes and mental retardation
    McElwee, C
    Bernard, S
    CURRENT OPINION IN PSYCHIATRY, 2002, 15 (05) : 469 - 475
12345