Recent progress in the development of derivatization reagents having a benzofurazan structure

被引：18
作者：
Santa, Tomofumi [1 ]
Fukushima, Takeshi [2 ]
Ichibangase, Tomoko [3 ]
Imai, Kazuhiro [3 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
[2] Univ Shizuoka, Sch Pharmaceut Sci, Div Bioanalyt Chem, Shizuoka 4228526, Japan
[3] Musashino Univ, Res Inst Pharmaceut Sci, Tokyo 2028585, Japan
来源：
BIOMEDICAL CHROMATOGRAPHY | 2008年 / 22卷 / 04期
关键词：
benzofurazan; 2,1,3-benzoxadiazole; derivatization reagent; fluorescence; mass spectrometry; high-performance liquid chromatography;
D O I：
10.1002/bmc.945
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Chemical derivatization is often used to enhance the delectability of the target compounds and to improve the separation efficiency in high-performance liquid chromatography (HPLC). In this review, we describe the recent progress in the development of derivatization reagents having a benzofurazan structure, namely, the fluorogenic reagents, water-soluble reagents, reagents for the analysis of peptides and proteins, and reagents for mass spectrometric detection. The application of these reagents to bio-samples is also briefly described. Copyright (c) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码：343 / 353
页数：11
相关论文
共 87 条
[1]  
ADUMA K, 2003, PHOTOCH PHOTOBIO SCI, V2, P443
[2]   Analysis of organic acid markers relevant to inherited metabolic diseases by ultra-performance liquid chromatography/tandem mass spectrometry as benzofurazan derivatives [J].
Al-Dirbashi, Osama Y. ;
Santa, Tomofumi ;
Al-Qahtani, Khalid ;
Al-Amoudi, Mohammed ;
Rashed, Mohamed S. .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 21 (13) :1984-1990
[3]   Derivatization of ethinylestradiol with dansyl chloride to enhance electrospray ionization: Application in trace analysis of ethinylestradiol in rhesus monkey plasma [J].
Anari, MR ;
Bakhtiar, R ;
Zhu, B ;
Huskey, S ;
Franklin, RB ;
Evans, DC .
ANALYTICAL CHEMISTRY, 2002, 74 (16) :4136-4144
[4]  
ASAMOTO H, IN PRESS BIOMEDICAL
[5]   Relating electrospray ionization response to nonpolar character of small peptides [J].
Cech, NB ;
Enke, CG .
ANALYTICAL CHEMISTRY, 2000, 72 (13) :2717-2723
[6]   Practical implications of some recent studies in electrospray ionization fundamentals [J].
Cech, NB ;
Enke, CG .
MASS SPECTROMETRY REVIEWS, 2001, 20 (06) :362-387
[7]   Predicting electrospray response from chromatographic retention time [J].
Cech, NB ;
Krone, JR ;
Enke, CG .
ANALYTICAL CHEMISTRY, 2001, 73 (02) :208-213
[8]   Selective 'in synthesis' labelling of peptides by fluorochromes [J].
Chersi, A ;
diModugno, F ;
Rosano, L .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1997, 1336 (01) :83-88
[9]   SENSITIVE DETERMINATION OF SALMON-CALCITONIN, BY MEANS OF PRECOLUMN DERIVATIZATION, HPLC AND FLUOROMETRIC-DETERMINATION [J].
FUKUDA, T ;
ISHIKAWA, K ;
IMAI, K .
BIOMEDICAL CHROMATOGRAPHY, 1995, 9 (01) :52-55
[10]   Recent progress in derivatization methods for LC and CE analysis [J].
Fukushima, T ;
Usui, N ;
Santa, T ;
Imai, K .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 30 (06) :1655-1687
123456789