Facile and Odorless One-Pot Process for the Synthesis of N-Substituted Thioamides via TsCl-Mediated Beckmann Rearrangement of Ketoximes

被引：7
|
作者：
Liu, Li-Feng [1 ]
An, Na [1 ]
Pi, Hong-Jun [1 ]
Ying, Jun [1 ]
Du, Wenting [1 ,2 ]
Deng, Wei-Ping [1 ]
机构：
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
[2] Zhejiang Med Coll, Dept Pharm, Hangzhou 310053, Zhejiang, Peoples R China
来源：
SYNLETT | 2011年 / 07期
关键词：
Beckmann rearrangement; thioamides; tosyl chloride; ketoximes; LAWESSONS REAGENT; THIONATION; AMIDES; CONVERSION; CATALYST; LACTAMS; MILD;
D O I：
10.1055/s-0030-1259720
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and odorless one-pot thionation process for the synthesis of N-substituted thioamides using chemically stable and inexpensive thiourea reagent via the Beckmann rearrangement of ketoximes, has been described.
引用
收藏
页码：979 / 981
页数：3
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