The Engineering of Brown Fat

被引：18

作者：

Christian, Mark ^{[1
]}

Parker, Malcolm G. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Inst Reprod & Dev Biol, London W12 0NN, England

来源：

JOURNAL OF MOLECULAR CELL BIOLOGY | 2010年 / 2卷 / 01期

关键词：

TRANSCRIPTIONAL COMPLEX; WHITE ADIPOCYTES; ADIPOSE-TISSUE; EXPRESSION; SWITCH;

D O I：

10.1093/jmcb/mjp035

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The developmental origins of brown adipose tissue and white adipose tissue are distinct, with brown adipocytes being derived from muscle precursors. PR domain containing 16, together with C/EBP beta, forms a lineage-switching transcriptional complex which promotes brown fat differentiation and suppresses muscle cell differentiation.

引用

页码：23 / 25

页数：3

共 10 条

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