Asymmetric Organocatalysis in Continuous Flow: Opportunities for Impacting Industrial Catalysis

被引:171
作者
Atodiresei, Iuliana [1 ]
Vila, Carlos [1 ]
Rueping, Magnus [1 ]
机构
[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
关键词
organocatalysis; photoredox catalysis; heterogeneous catalysis; immobilization; microreactor; SOLID-SUPPORTED ORGANOCATALYST; ALPHA-AMINATION; ALDOL; BATCH; PROLINE; LIGHT; OPTIMIZATION; ALDEHYDES; REACTOR;
D O I
10.1021/acscatal.5b00002
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The review highlights the different advantages associated with organocatalytic transformations performed in continuous-flow systems and presents the reactions which have been successfully achieved to date. Particular focus is placed on the comparison between batch and flow applications in order to show the advantages and disadvantages and to demonstrate the great potential for applying organocatalysis as well as combined organ and photoredox catalyzed reactions in continuous flow.
引用
收藏
页码:1972 / 1985
页数:14
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