Molecular cloning and characterisation of a mouse gene encoding an isoform of the neuronal cyclin-dependent kinase 5 (CDK5) activator

被引：9

作者：

Nildén, F ^{[1
]}

Bäckström, A ^{[1
]}

Bark, C ^{[1
]}

机构：

[1] Univ Uppsala, BMC, Dept Dev Neurosci, S-75123 Uppsala, Sweden

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1398卷 / 03期

关键词：

CDK5; activator; Cdc2-like protein kinase; neuronal protein; p35; p39; gene;

D O I：

10.1016/S0167-4781(98)00073-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated and characterised the mouse gene for the p39 activator, designated p39is, which encodes a protein of 369 amino acids. The mouse p39 protein exhibits 95% amino acid identity to a previously characterised human p39 cDNA and the novel gene sequence corresponds to a single genomic locus in mouse. The p39is mRNA is highly expressed in the mouse central nervous system. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：371 / 376

页数：6

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