Economic burden in treated Japanese patients with relapsed/refractory large B-cell lymphoma

被引:8
作者
Tsutsue, Saaya [1 ]
Makita, Shinichi [2 ]
Yi, Jingbo [3 ]
Crawford, Bruce [3 ]
机构
[1] Bristol Myers Squibb, Chiyoda Ku, JP Tower,2-7-2 Marunouchi, Tokyo 1007010, Japan
[2] Natl Canc Ctr, Tokyo 1040045, Japan
[3] Syneos Hlth, Tokyo 1030027, Japan
关键词
cost; COVID-19; database study; diffuse large B-cell lymphoma; Japanese; refractory; relapse; retrospective; salvage chemotherapy; ELDERLY-PATIENTS; SINGLE-ARM; TRANSPLANTATION; THERAPY; RISK; EPIDEMIOLOGY; CHEMOTHERAPY; PROGRESSION; GUIDELINES; COVID-19;
D O I
10.2217/fon-2021-0400
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aim: To understand the economic burden of relapsed and refractory large B-cell lymphoma patients in Japan treated with salvage chemotherapy. Patients & methods: Patients who received systemic therapy after first-line treatment were analyzed to assess its associated cost and resource use using a retrospective claims database. The impact of COVID-19 was assessed separately. Results & conclusion: This study identified 2927 and 1085 patients in the second- (2L) and third-line (3L) cohorts. The median ages for the 2L and 3L cohorts were 71 and 70 years, respectively, with Charlson Comorbidity Score of 3. A majority of the patients had limited stem cell transplant due to advanced age. Median lengths of inpatient stay for the 2L and 3L cohorts were 118 and 116 days, respectively. The majority of costs were attributed to inpatient costs, and limited COVID-19 impact was observed in this study.
引用
收藏
页码:4511 / 4525
页数:15
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