additive manufacturing;
bone scaffolds;
finite element analysis;
mechanical analysis;
D O I:
10.3390/ma14133546
中图分类号:
O64 [物理化学(理论化学)、化学物理学];
学科分类号:
070304 ;
081704 ;
摘要:
Ideal bone scaffolds for tissue engineering should be highly porous allowing cell attachment, spreading, and differentiation and presenting appropriate biomechanical properties. These antagonistic characteristics usually require extensive experimental work to achieve optimised balanced properties. This paper presents a simulation approach to determine the mechanical behaviour of bone scaffolds allowing the compressive modulus and the deformation mechanisms to be predicted. Polycaprolactone scaffolds with regular square pores and different porosities were considered. Scaffolds were also printed using an extrusion-based additive manufacturing and assessed under compressive loads. Similar designs were used for both simulation and fabrication steps. A good correlation between numerical and experimental results was obtained, highlighting the suitability of the simulation tool for the mechanical design of 3D-printed bone scaffolds.
机构:
Bursa Technical University, Department of Mechanical Engineering, BursaBursa Technical University, Department of Mechanical Engineering, Bursa
Senaysoy, Safa
Ilhan, Recep
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机构:
Bursa Technical University, Department of Mechanical Engineering, Bursa
Bursa Technical University, Department of Polymer Materials Engineering, BursaBursa Technical University, Department of Mechanical Engineering, Bursa
Ilhan, Recep
Lekesiz, Huseyin
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机构:
Bursa Technical University, Department of Mechanical Engineering, BursaBursa Technical University, Department of Mechanical Engineering, Bursa
机构:
KTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden
KTH Royal Inst Technol, Dept Solid Mech, Stockholm, SwedenKTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden
Liu, Hailong
Ahlinder, Astrid
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机构:
KTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, SwedenKTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden
Ahlinder, Astrid
Yassin, Mohammed A.
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机构:
Univ Bergen, Dept Clin Dent, Bergen, NorwayKTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden
Yassin, Mohammed A.
Finne-Wistrand, Anna
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机构:
KTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, SwedenKTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden
Finne-Wistrand, Anna
Gasser, T. Christian
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机构:
KTH Royal Inst Technol, Dept Solid Mech, Stockholm, SwedenKTH Royal Inst Technol, Dept Fibre & Polymer Technol, Stockholm, Sweden