Enantioselective radical addition/trapping reactions with α,β-disubstituted unsaturated imides.: Synthesis of anti-propionate aldols

被引：67

作者：

Sibi, MP ^{[1
]}

Petrovic, G ^{[1
]}

Zimmerman, J ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 08期

关键词：

D O I：

10.1021/ja043371e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This manuscript describes a highly diastereo- and enantioselective intermolecular radical addition/hydrogen atom transfer to α,β-disubstituted enoates. Additionally, we show that anti-propionate aldol-like products can be easily prepared from α-methyl-β-acyloxyenoates in good yields and high diastereo- and enantioselectivities. Copyright © 2005 American Chemical Society.

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页码：2390 / 2391

页数：2

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