Quantitative Techniques in PET-CT Imaging

被引：15
作者：
Basu, Sandip [6 ]
Zaidi, Habib [3 ,4 ,5 ]
Holm, Soren [2 ]
Alavi, Abass [1 ]
机构：
[1] Hosp Univ Penn, Dept Radiol, Div Nucl Med, Philadelphia, PA 19104 USA
[2] Univ Copenhagen, Rigshosp, DK-1168 Copenhagen, Denmark
[3] Univ Groningen, Univ Med Ctr Gronigen, Dept Nucl Med & Mol Imaging, NL-9700 RB Groningen, Netherlands
[4] Univ Geneva, Geneva Neurosci Ctr, CH-1211 Geneva, Switzerland
[5] Univ Hosp Geneva, Div Nucl Med & Mol Imaging, CH-1211 Geneva, Switzerland
[6] Tata Mem Hosp Annexe, Radiat Med Ctr BARC, Bombay 400012, Maharashtra, India
来源：
CURRENT MEDICAL IMAGING REVIEWS | 2011年 / 7卷 / 03期
基金：
瑞士国家科学基金会;
关键词：
Hybrid imaging; positron emission tomography (PET); quantitative imaging; standardized uptake value (SUV); POSITRON-EMISSION-TOMOGRAPHY; CEREBRAL GLUCOSE-UTILIZATION; STANDARDIZED UPTAKE VALUES; PARTIAL VOLUME CORRECTION; POINT F-18-FDG PET; CEREBROSPINAL-FLUID VOLUMES; SURFACE AREA CORRECTION; FDG LUMPED CONSTANT; HIGH-GRADE GLIOMA; BREAST-CANCER;
D O I：
10.2174/157340511796411186
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
The appearance of hybrid PET/CT scanners has made quantitative whole body scanning of radioactive tracers feasible. This paper deals with the novel concepts for assessing global organ function and disease activity based on combined functional (PET) and structural (CT or MR) imaging techniques, their advantages over current quantitative techniques and their potential clinical applications in the management of various diseases. First the complicated kinetic modeling and methods for calculation of the standardized uptake value (SUV) that have been utilized in the practice of clinical PET are briefly described. Subsequently we discuss the quantitative concepts in PET-CT imaging that have been developed in recent years: (a) SUV analysis in the dual-time point and delayed PET imaging, (b) partial volume correction of SUV for small lesions (c) assessment of global metabolic activity in the whole organ or of diseased sites and (d) the novel image segmentation techniques with FDG-PET and newer tracers to precisely define the diseased or intended normal tissue which is of great value for image guided radiation therapy.
引用
收藏
页码：216 / 233
页数：18
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