An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anti-cancer Activity

被引:21
作者
Naikoo, Gowhar [1 ]
Al-Mashali, Fatema [2 ]
Arshad, Fareeha [3 ]
AL-Maashani, Naema [2 ]
Hassan, Israr U. [4 ]
AL-Baraami, Zamzam [2 ]
Faruck, Lukmanul H. [3 ]
Qurashi, Ahsanulhaq [5 ]
Ahmed, Waqar
Asiri, Abdullah M. [6 ]
Aljabali, Alaa A. [7 ]
Bakshi, Hamid A. [8 ]
Tambuwala, Murtaza M. [9 ]
机构
[1] Dhofar Univ, Coll Arts & Appl Sci, Dept Math & Sci, Salalah 211, Oman
[2] Dhofar Univ, Dept Chem Engn, Coll Engn, Salalah 211, Oman
[3] Aligarh Muslim Univ, Dept Biochem, Aligarh, UP, India
[4] Dhofar Univ, Coll Engn, Salalah 211, Oman
[5] Univ Minnesota, Masonic Canc Ctr, Dept Urol, Minneapolis, MN 55455 USA
[6] Univ Lincoln, Coll Sci, Sch Math & Phys, Lincoln LN6 7TS, England
[7] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia
[8] Yarmouk Univ, Dept Pharmaceut & Pharmaceut Technol, Fac Pharm, Irbid 566, Jordan
[9] Ulster Univ, Sch Pharm & Pharmaceut Sci, Coleraine BT52 1SA, Londonderry, North Ireland
关键词
Cancer; nanomedicine; copper nanoparticles; diagnostics; therapeutics; cancer treatment; nanomaterials; DRUG-DELIVERY SYSTEMS; BREAST-CANCER CELLS; OXIDE NANOPARTICLES; GREEN SYNTHESIS; ANTIMICROBIAL ACTIVITY; CU NANOPARTICLES; ASCORBIC-ACID; STEM-CELLS; THERAPY; CYTOTOXICITY;
D O I
10.2174/1381612827666210804100303
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In this review, we summarised the different methods for copper nanoparticle synthesis, including green methods. We highlighted that the synthesis of the copper nanoparticles from green sources is preferable as they serve as stable and reducing entities. Furthermore, we critically reviewed the effectiveness of cop-per-based nanoparticles in oncogenic treatments emphasizing breast, lung, colorectal, and skin cancers. Finally, we have summarised the recent progress made in copper-based nanoparticles and their applications to amplify and rectify present cancer treatment options. The synthesis, characterization, stabilization, and functionalization techniques of various copper-based nanoparticles have also been highlighted in each section. In conclusion, the review provides the outlook of copper nanoparticles in cancer diagnostics and therapeutics.
引用
收藏
页码:4416 / 4432
页数:17
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