A comparison of lateral diffusion in supported lipid monolayers and bilayers

被引：15

作者：

Babayco, Christopher B. ^{[2
]}

Turgut, Sennur ^{[1
]}

Smith, Andreia Michelle ^{[3
]}

Sanii, Babak ^{[1
]}

Land, Donald ^{[2
]}

Parikh, Atul N. ^{[1
,3
]}

机构：

[1] Dept Appl Sci, Davis, CA 95616 USA

[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

[3] Biophys Grad Grp, Davis, CA 95616 USA

来源：

SOFT MATTER | 2010年 / 6卷 / 23期

关键词：

PHASE-TRANSITIONS; PHYSICAL-PROPERTIES; PHOSPHOLIPID MONOLAYERS; BIOLOGICAL-MEMBRANES; CHOLESTEROL; ASYMMETRY; PRESSURE; VESICLES; BEHAVIOR;

D O I：

10.1039/c0sm00643b

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Lipid monolayers and bilayers exist in distinct physical states differentiated by the differences in the manner in which translational fluidity relates to their phase transition and how cholesterol influences the two. Work presented here suggests that intra-leaflet diffusion and cholesterol interactions are modulated by the nature of inter-leaflet coupling. Our results also provide an important practical caveat in the comparisons of membrane physical properties deduced using the two, mono- and bilayer, model membrane configurations.

引用

页码：5877 / 5881

页数：5

共 41 条

[1] LATERAL DIFFUSION IN THE LIQUID-PHASES OF DIMYRISTOYLPHOSPHATIDYLCHOLINE CHOLESTEROL LIPID BILAYERS - A FREE-VOLUME ANALYSIS [J].