Synthesis of a structure containing three N-fused heterocycles with very high bond-forming through a one-pot reaction

被引：5
作者：
Alizadeh-Kouzehrash, Meysam [1 ]
Rahmati, Abbas [1 ]
机构：
[1] Univ Isfahan, Dept Chem, POB 81746-73441, Esfahan, Iran
来源：
TETRAHEDRON | 2020年 / 76卷 / 07期
关键词：
N-fused heterocycles; Isoindoline; Pyrazole; Quinazoline; ANTIMICROBIAL ACTIVITY; DERIVATIVES; RECEPTOR; SOLVENT; 3-COMPONENT; NUCLEOSIDES; BATRACYLIN; INHIBITORS; EFFICIENT; ANALOGS;
D O I：
10.1016/j.tet.2020.130923
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Some new N-fused heterocyclic compounds have been simply synthesized via a mild and efficient one-pot two-step four-component reaction between hydrazine hydrate, various 3-oxoalkanonitriles, 2-phthaldehydic acid and different CH-acids in ethanol, in the presence of 4-toluenesulfonic acid as catalyst. A large number of bonds (9 bonds) are formed during the transformation. (C) 2020 Elsevier Ltd. All rights reserved.
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页数：8
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